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S1PL-IN-31

S1PL-IN-31 is a dual S1P lyase (IC50=210 nM) and Smoothened receptor antagonist (IC50=440 nM) . It demonstrates in vivo efficacy in an EAE rat model, reducing lymphocytic infiltration and attenuating disease symptoms, highlighting its research utility in neuroinflammation and autoimmune studies.

Product Specifications

CAS Number

1538574-95-6

Field of Research

Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Smiles

C[C@@H] (N (C1=CC=C (C=N1) C#N) CC2) CN2C3=NN=C (C4=C3C=C (C=C4) Cl) CC5=CC=CC=C5

Molecular Formula

C26H23ClN6

Molecular Weight

454.95

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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