Glutaminase C Inhibitor 11
Glutaminase C Inhibitor 11 is a potent and selective GAC inhibitor with an EC50 of 10.64 nM. It demonstrates robust anti-tumor activity, inhibiting A549 NSCLC cell viability (IC50 = 4.025 nM), colony formation, and glutamate production in vitro, and significantly reducing tumor growth in A549 xenograft models at 100 mg/kg.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (CC1=CC=CC (OC2=CC=CC=C2) =C1) NC3=NN=C (N[C@@H]4CCN (C5=CC=CN=N5) C4) S3
Molecular Formula
C24H23N7O2S
Molecular Weight
473.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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