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Phenyl-glutarimide 4'-piperazine

This piperazine-functionalized cereblon ligand, Phenyl-glutarimide 4'-piperazine, enables the creation of PG-PROTAC degraders with superior hydrolytic stability and potency over traditional IMiD-based analogs. It serves as a key chemical scaffold for developing targeted protein degradation tools in both cellular and preclinical research.

Product Specifications

CAS Number

2902651-89-0

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C1CCC (C2=CC=C (N3CCNCC3) C=C2) C (N1) =O.Cl.Cl

Molecular Formula

C15H19N3O2.2HCl

Molecular Weight

346.25

Storage Conditions

-20°C

Notes

For research use only.

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