EIF4A i28
EIF4A i28 is a potent, RNA-competitive inhibitor of the eukaryotic initiation factor 4A (eIF4A) with an IC50 of 8.60 μM in ATPase assays. It demonstrates potent anti-proliferative activity in BJAB Burkitt lymphoma cells (EC50 = 0.46 μM) and serves as a valuable chemical probe for studying translation initiation in cancer research.
Product Specifications
CAS Number
2861994-92-3
Smiles
CCCCC1=CC=C (C2=CC=C (C3=NC4=CC=C (C=C4C (C (O) =O) =C3) [N+] ([O-]) =O) O2) C=C1
Molecular Formula
C24H20N2O5
Molecular Weight
416.43
Storage Conditions
-20°C
Notes
For research use only.
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