TAT-PDHPS1
TAT-PDHPS1 is a cell-permeable peptide inhibitor of YAP signaling that acts by binding PTPA to activate PP2A, leading to YAP phosphorylation. It has demonstrated efficacy in inhibiting ovarian cancer cell proliferation in vitro and reducing tumor growth in mouse xenograft models, supporting its use in oncology research.
Product Specifications
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCCCN) C (N[C@@H] (CCCCN) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCC (N) =O) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCCNC (N) =N) C (N1[C@@H] (CCC1) C (N2[C@@H] (CCC2) C (N[C@@H] (CCC (N) =O) C (N[C@@H] (CCC (N) =O) C (N[C@@H] ([C@@H] (C) CC) C (N[C@@H] (C) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] (C) C (N[C@@H] (CO) C (N[C@@H] (C) C (N[C@@H] (C) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] (C) C (N[C@@H] (C) C (N[C@@H] (C) C (N[C@@H] ([C@@H] (C) CC) C (NCC (N[C@@H] (C) C (N[C@@H] ([C@H] (O) C) C (N3[C@@H] (CCC3) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (C) C (N[C@@H] (CCCCN) C (O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) CN
Molecular Formula
C156H280N62O45
Molecular Weight
3744.32
Storage Conditions
-20°C
Notes
For research use only.
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