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XIE62-1004

XIE62-1004 is a specific small molecule that binds the p62 ZZ domain, inducing p62 self-aggregation and LC3 interaction to drive selective autophagy. It effectively degrades cargo like mutant huntingtin in vitro and functions within AUTAC systems, demonstrating utility in autophagy research both in cellular and animal models.

Product Specifications

CAS Number

2421146-32-7

Field of Research

Cell Biology

Smiles

Cl.OCCNCC1=CC=C (OCC=2C=CC=CC2) C (OCC=3C=CC=CC3) =C1

Molecular Formula

C23H25NO3.HCl

Molecular Weight

399.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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