XIE62-1004
XIE62-1004 is a specific small molecule that binds the p62 ZZ domain, inducing p62 self-aggregation and LC3 interaction to drive selective autophagy. It effectively degrades cargo like mutant huntingtin in vitro and functions within AUTAC systems, demonstrating utility in autophagy research both in cellular and animal models.
Product Specifications
CAS Number
2421146-32-7
Field of Research
Cell Biology
Smiles
Cl.OCCNCC1=CC=C (OCC=2C=CC=CC2) C (OCC=3C=CC=CC3) =C1
Molecular Formula
C23H25NO3.HCl
Molecular Weight
399.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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