Sultamicillin

Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity[1].

Product Specifications

CAS Number

[76497-13-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sultamicillin.html

Purity

98.32

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OCOC([C@H](N1C2=O)C(C)(S[C@@]1([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)[H])C)=O)[C@H](N45)C(C)(S([C@@]4(CC5=O)[H])(=O)=O)C

Molecular Formula

C25H30N4O9S2

Molecular Weight

594.66

Precautions

H315, H319, H320

References & Citations

[1]Friedel HA, et al. Sultamicillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1989 Apr;37 (4) :491-522.|[2]English AR, et al. Pharmacokinetics of sultamicillin in mice, rats, and dogs. Antimicrob Agents Chemother. 1984 May;25 (5) :599-602.|[3]Assfalg V, et al. Combined immunosuppressive and antibiotic therapy improves bacterial clearance and survival of polymicrobial septic peritonitis. Shock. 2010 Feb;33 (2) :155-61. |[4]Qin HL, et al. Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA) . Eur J Med Chem. 2020 May 15;194:112245.