ACHP
ACHP (IKK-2 Inhibitor VIII) is a selective IKK-α/β inhibitor that blocks NF-κB activation. It exhibits anti-HIV-1 activity by suppressing TNF-α-induced recruitment of NF-κB (p65) to the HIV-1 LTR, thereby inhibiting viral gene expression. This compound is a valuable tool for studying NF-κB signaling in inflammation and viral pathogenesis research.
Product Specifications
CAS Number
406208-42-2
Product Name Alternative
IκB, IKK-2 Inhibitor VIII, IkB/IKK, IKK, IkB
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.66% (May vary between batches)
Solubility
DMSO:5 mg/mL (13.72 mM)
Smiles
N#CC1=C (N=C (C=C1C2CCNCC2) C=3C (O) =CC=CC3OCC4CC4) N
Molecular Formula
C21H24N4O2
Molecular Weight
364.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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