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Pumafentrine

Pumafentrine (BY 343) is a dual PDE3 and PDE4 inhibitor. It has demonstrated efficacy in murine models of experimental colitis, lowering clinical disease scores and suppressing TNF expression. This small molecule is a valuable research tool for studying PDE inhibition in inflammatory bowel disease and related immunological pathways.

Product Specifications

CAS Number

207993-12-2

Product Name Alternative

BY 343, PDE3, PDE4

Field of Research

Metabolism Research

Purity

99.77% (May vary between batches)

Solubility

DMSO:50 mg/mL (104.68 mM)

Smiles

O (C) C=1C=C2C ([C@]3 ([C@@] (N=C2C4=CC=C (C (N (C (C) C) C (C) C) =O) C=C4) (CCN (C) C3) [H]) [H]) =CC1OCC

Molecular Formula

C29H39N3O3

Molecular Weight

477.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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