4-Chloro-L-phenylalanine
4-Chloro-L-phenylalanine (L-PCPA) is a non-specific inhibitor of tryptophan hydroxylase (TPH1/TPH2), the rate-limiting enzyme in serotonin biosynthesis. It is widely used in neuroscience research to deplete 5-HT levels for studying serotonergic function in both in vivo animal models and in vitro cellular assays.
Product Specifications
CAS Number
14173-39-8
Product Name Alternative
L-4-Chlorophenylalanine, L-PCPA, 5-HT, 5HTReceptor, 5HT Receptor, 4-Chloro-L-phenylalanine
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
98.04% (May vary between batches)
Solubility
H2O:10 mg/mL (50.09 mM)
Smiles
N[C@@H] (Cc1ccc (Cl) cc1) C (O) =O
Molecular Formula
C9H10ClNO2
Molecular Weight
199.63
Storage Conditions
-20°C
Notes
For research use only.
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