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4-Chloro-L-phenylalanine

4-Chloro-L-phenylalanine (L-PCPA) is a non-specific inhibitor of tryptophan hydroxylase (TPH1/TPH2), the rate-limiting enzyme in serotonin biosynthesis. It is widely used in neuroscience research to deplete 5-HT levels for studying serotonergic function in both in vivo animal models and in vitro cellular assays.

Product Specifications

CAS Number

14173-39-8

Product Name Alternative

L-4-Chlorophenylalanine, L-PCPA, 5-HT, 5HTReceptor, 5HT Receptor, 4-Chloro-L-phenylalanine

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

98.04% (May vary between batches)

Solubility

H2O:10 mg/mL (50.09 mM)

Smiles

N[C@@H] (Cc1ccc (Cl) cc1) C (O) =O

Molecular Formula

C9H10ClNO2

Molecular Weight

199.63

Storage Conditions

-20°C

Notes

For research use only.

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