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GPX4-IN-5

GPX4-IN-5 is a potent covalent inhibitor of glutathione peroxidase 4 (GPX4) with an IC50 of 0.12 μM. It triggers ferroptosis and demonstrates antitumor activity, making it a valuable research tool for studying and targeting triple-negative breast cancer (TNBC) in both cellular and animal models.

Product Specifications

CAS Number

2922824-09-5

Product Name Alternative

Gpx4, GPX4IN5

Field of Research

Cell Biology, Metabolism Research

Purity

99.58% (May vary between batches)

Solubility

DMSO:80 mg/mL (209.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.64 mM)

Smiles

O=C (N (C1=CC=C2OCCOC2=C1) C3=CC (OC) =C (F) C (OC) =C3) CCl

Molecular Formula

C18H17ClFNO5

Molecular Weight

381.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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