GPX4-IN-5
GPX4-IN-5 is a potent covalent inhibitor of glutathione peroxidase 4 (GPX4) with an IC50 of 0.12 μM. It triggers ferroptosis and demonstrates antitumor activity, making it a valuable research tool for studying and targeting triple-negative breast cancer (TNBC) in both cellular and animal models.
Product Specifications
CAS Number
2922824-09-5
Product Name Alternative
Gpx4, GPX4IN5
Field of Research
Cell Biology, Metabolism Research
Purity
99.58% (May vary between batches)
Solubility
DMSO:80 mg/mL (209.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.64 mM)
Smiles
O=C (N (C1=CC=C2OCCOC2=C1) C3=CC (OC) =C (F) C (OC) =C3) CCl
Molecular Formula
C18H17ClFNO5
Molecular Weight
381.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
