GPX4-IN-6
GPX4-IN-6 is a potent covalent inhibitor of glutathione peroxidase 4 (GPX4) with an IC50 of 0.12 μM. It triggers ferroptosis and demonstrates antitumor activity, making it a valuable research tool for studying and targeting triple-negative breast cancer (TNBC) in both cellular and animal models.
Product Specifications
CAS Number
2922824-07-3
Product Name Alternative
GPX4IN6, Gpx4
Field of Research
Cell Biology, Metabolism Research
Purity
99.54% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.69 mM) ; DMSO:30 mg/mL (70.38 mM)
Smiles
O=C (N (C1=CC=C2OCCOC2=C1) C3=CC (OC) =C (F) C (OC) =C3) CBr
Molecular Formula
C18H17BrFNO5
Molecular Weight
426.23
Storage Conditions
-20°C
Notes
For research use only.
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