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GPX4-IN-6

GPX4-IN-6 is a potent covalent inhibitor of glutathione peroxidase 4 (GPX4) with an IC50 of 0.12 μM. It triggers ferroptosis and demonstrates antitumor activity, making it a valuable research tool for studying and targeting triple-negative breast cancer (TNBC) in both cellular and animal models.

Product Specifications

CAS Number

2922824-07-3

Product Name Alternative

GPX4IN6, Gpx4

Field of Research

Cell Biology, Metabolism Research

Purity

99.54% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.69 mM) ; DMSO:30 mg/mL (70.38 mM)

Smiles

O=C (N (C1=CC=C2OCCOC2=C1) C3=CC (OC) =C (F) C (OC) =C3) CBr

Molecular Formula

C18H17BrFNO5

Molecular Weight

426.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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