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Trimethylamine N-oxide

Trimethylamine N-oxide (TMAO) is a dietary metabolite linked to gut flora that promotes cardiac fibrosis. It activates inflammatory pathways like ROS/NLRP3 and drives fibroblast differentiation via TGF-β/Smad2 signaling, making it a valuable tool for modeling fibrosis in both in vitro and in vivo research.

Product Specifications

CAS Number

1184-78-7

Product Name Alternative

Reactive Oxygen Species, ReactiveOxygenSpecies, Smad, Trimethylamine N oxide, Trimethylamine Noxide, Trimethylamine N-oxide, TGF-b/Smad, TGFb, TGFβ, TGF-β/Smad, TGF-beta, TGFbeta, TGF-beta/Smad, TGFbeta/Smad, NOD-like Receptor, NOD-like Receptor (NLR), NODlike Receptor (NLR), NODlikeReceptor, NODlikeReceptor (NLR), NLR, Metabolism

Field of Research

Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

H2O:10 mg/mL (133.14 mM) ; DMSO:125 mg/mL (1664.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (26.63 mM)

Smiles

C[N+] (C) (C) [O-]

Molecular Formula

C3H9NO

Molecular Weight

75.11

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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