Trimethylamine N-oxide
Trimethylamine N-oxide (TMAO) is a dietary metabolite linked to gut flora that promotes cardiac fibrosis. It activates inflammatory pathways like ROS/NLRP3 and drives fibroblast differentiation via TGF-β/Smad2 signaling, making it a valuable tool for modeling fibrosis in both in vitro and in vivo research.
Product Specifications
CAS Number
1184-78-7
Product Name Alternative
Reactive Oxygen Species, ReactiveOxygenSpecies, Smad, Trimethylamine N oxide, Trimethylamine Noxide, Trimethylamine N-oxide, TGF-b/Smad, TGFb, TGFβ, TGF-β/Smad, TGF-beta, TGFbeta, TGF-beta/Smad, TGFbeta/Smad, NOD-like Receptor, NOD-like Receptor (NLR), NODlike Receptor (NLR), NODlikeReceptor, NODlikeReceptor (NLR), NLR, Metabolism
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
H2O:10 mg/mL (133.14 mM) ; DMSO:125 mg/mL (1664.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (26.63 mM)
Smiles
C[N+] (C) (C) [O-]
Molecular Formula
C3H9NO
Molecular Weight
75.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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