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NAT1-IN-1

NAT1-IN-1 (compound 350) is a potent N-acetyltransferase 1 (NAT1) -targeted inhibitor, with an IC50 of 44 nM. NAT1-IN-1 can be used for the research of hypermetabolic diseases such as amyotrophic lateral sclerosis, cancer cachexia, and sepsis[1].

Product Specifications

UNSPSC

12352005

Target

Histone Acetyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/nat1-in-1.html

Purity

99.77

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=S(NC1=C(NC2=CC=C(CC(O)=O)C=C2)C(C3=CC=CC=C3C1=O)=O)(C4=CC=CC=C4)=O

Molecular Formula

C24H18N2O6S

Molecular Weight

462.47

References & Citations

[1]Chandra Choudhury, et al. Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular Respiration.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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