CLK1-IN-3
CLK1-IN-3 is a potent and selective inhibitor of CLK1 (IC50 = 5 nM), with significant activity against CLK2 and CLK4. It induces autophagy in vitro and shows potential for research into acute liver injury (ALI) prevention and treatment.
Product Specifications
CAS Number
2922550-28-3
Product Name Alternative
Autophagy, CLK4, CLK1-IN-3, CLK2, CLK1, Benzamide, N[3 (5fluoro3pyridinyl) 1Hpyrrolo[2,3b]pyridin5yl]4 (4methyl1piperazinyl), DYRK1A
Field of Research
Cell Biology, Signal Transduction
Purity
98.46% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.65 mM) ; DMSO:55 mg/mL (127.76 mM)
Smiles
O=C (NC=1C=NC=2NC=C (C=3C=NC=C (F) C3) C2C1) C4=CC=C (C=C4) N5CCN (C) CC5
Molecular Formula
C24H23FN6O
Molecular Weight
430.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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