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SZM-1209

SZM-1209 is a potent, orally active, and specific RIPK1 inhibitor with a Kd of 85 nM. It exhibits potent anti-necroptotic activity (EC50 = 22.4 ± 8.1 nM) and has demonstrated therapeutic efficacy in preclinical models of systemic inflammatory response syndrome (SIRS) and acute lung injury (ALI) .

Product Specifications

CAS Number

2919801-86-6

Field of Research

Cell Biology, Signal Transduction

Molecular Formula

C31H29F5N4O5S2

Molecular Weight

696.71

Storage Conditions

-20°C

Notes

For research use only.

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