EN450
EN450 is a cysteine-responsive covalent degrader that targets NF-κB, dependent on Cullin E3 ligase and proteasome activity. It exhibits antiproliferative effects and is a research tool for studying leukemia, with applications in both in vitro and in vivo cancer biology experiments.
Product Specifications
CAS Number
793719-01-4
Product Name Alternative
N-[2-Chloro-5- (dimethylsulfamoyl) phenyl]prop-2-enamide
Field of Research
Protein Biochemistry
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to at least 80 mg/ml)
Smiles
O=C (C=C) NC1=CC (=CC=C1Cl) S (=O) (=O) N (C) C
Molecular Formula
C11H13ClN2O3S
Molecular Weight
288.8
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (2-Chloro-5- (N, N-dimethylsulfamoyl) phenyl) acrylamide
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