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Cbl-b-IN-5

Cbl-b-IN-5 is a potent and selective small molecule inhibitor of the E3 ubiquitin ligase Cbl-b, exhibiting IC50 values in the low micromolar range (3-10 μM) . It serves as a valuable research tool for investigating the role of Cbl-b in immunological disorders and cancer biology, facilitating both in vitro cellular studies and in vivo disease model research.

Product Specifications

CAS Number

2368835-59-8

Product Name Alternative

Cbl, CblbIN5, Cbl-b-IN-5

Field of Research

Cancer Biology, Protein Biochemistry

Purity

99.93% (May vary between batches)

Solubility

DMSO:50 mg/mL (147.31 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.89 mM)

Smiles

O=C (NC1=CC=CC (=C1) C (SC2=NN=CN2C) C) C3=NC=CC=C3

Molecular Formula

C17H17N5OS

Molecular Weight

339.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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