Cbl-b-IN-5
Cbl-b-IN-5 is a potent and selective small molecule inhibitor of the E3 ubiquitin ligase Cbl-b, exhibiting IC50 values in the low micromolar range (3-10 μM) . It serves as a valuable research tool for investigating the role of Cbl-b in immunological disorders and cancer biology, facilitating both in vitro cellular studies and in vivo disease model research.
Product Specifications
CAS Number
2368835-59-8
Product Name Alternative
Cbl, CblbIN5, Cbl-b-IN-5
Field of Research
Cancer Biology, Protein Biochemistry
Purity
99.93% (May vary between batches)
Solubility
DMSO:50 mg/mL (147.31 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.89 mM)
Smiles
O=C (NC1=CC=CC (=C1) C (SC2=NN=CN2C) C) C3=NC=CC=C3
Molecular Formula
C17H17N5OS
Molecular Weight
339.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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