P-gb-IN-1
P-gb-IN-1 is a potent and low-toxicity P-glycoprotein (P-gp) inhibitor that acts by binding to residues Asn721 and Met986, effectively reversing multidrug resistance. This small molecule is a valuable research tool for studying drug efflux mechanisms and overcoming chemoresistance in vitro, particularly in models like MCF-7/ADR cells.
Product Specifications
CAS Number
2632874-49-6
Product Name Alternative
Pgp, P-gp, PgbIN1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.58% (May vary between batches)
Solubility
DMSO:50 mg/mL (97.55 mM)
Smiles
O=C (NC=1C=CC (=CC1) C=2OC (=CC2) C (=O) N3CC4=CC (OC) =C (OC) C=C4CC3) C5=CC=C (OC) C=C5
Molecular Formula
C30H28N2O6
Molecular Weight
512.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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