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LMTK3-IN-1

LMTK3-IN-1 is a potent, ATP-competitive inhibitor of Lemur Tyrosine Kinase 3 (Kd=2.5 μM) that induces its degradation via the ubiquitin-proteasome pathway. It demonstrates pro-apoptotic and anticancer activity in breast cancer cell lines (10-20 μM) and has shown efficacy in preclinical in vivo models of breast cancer.

Product Specifications

CAS Number

2764850-23-7

Product Name Alternative

LMTK3IN1, LMTK3-IN-1, HGFR, cMet, c-Met/HGFR, c-Met, cMet/HGFR

Field of Research

Signal Transduction

Purity

99.58% (May vary between batches)

Solubility

DMSO:9.17 mg/mL (25.74 mM)

Smiles

FC (F) (F) OC1=CC=CC (=C1) C2=CN=C3C=CC (=NN32) C=4C=CN=CC4

Molecular Formula

C18H11F3N4O

Molecular Weight

356.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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