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BMS-684

BMS-684 is a potent and selective DGKα inhibitor (IC50: 15 nM) that also targets DGKβ and γ. Its inhibition of DGK isoforms enhances T-cell activation, supporting its investigation in antitumor immunity and immune-related disease research in both cellular and animal models.

Product Specifications

CAS Number

313552-29-3

Product Name Alternative

BMS684, DGK

Purity

99.64% (May vary between batches)

Solubility

DMSO:7.14 mg/mL (15.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.2 mM)

Smiles

O=C1C ([N+] ([O-]) =O) =C (N2CCN (C (C3=CC=CC=C3) C4=CC=CC=C4) CC2) C5=C (N1C) C=CC=C5

Molecular Formula

C27H26N4O3

Molecular Weight

454.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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