BMS-684
BMS-684 is a potent and selective DGKα inhibitor (IC50: 15 nM) that also targets DGKβ and γ. Its inhibition of DGK isoforms enhances T-cell activation, supporting its investigation in antitumor immunity and immune-related disease research in both cellular and animal models.
Product Specifications
CAS Number
313552-29-3
Product Name Alternative
BMS684, DGK
Purity
99.64% (May vary between batches)
Solubility
DMSO:7.14 mg/mL (15.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.2 mM)
Smiles
O=C1C ([N+] ([O-]) =O) =C (N2CCN (C (C3=CC=CC=C3) C4=CC=CC=C4) CC2) C5=C (N1C) C=CC=C5
Molecular Formula
C27H26N4O3
Molecular Weight
454.52
Storage Conditions
-20°C
Notes
For research use only.
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