Zamaporvint
Zamaporvint (RXC004) is a potent, orally bioavailable porcupine inhibitor that suppresses Wnt signaling by blocking Wnt ligand palmitoylation and secretion. It has demonstrated anti-proliferative effects across diverse cancer cell lines in vitro and has shown anti-tumor activity in preclinical in vivo models.
Product Specifications
CAS Number
1900754-56-4
Product Name Alternative
Wnt, RXC 004, RXC004, RXC-004, Zamaporvint
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.50% (May vary between batches)
Solubility
DMSO:100 mg/mL (227.59 mM)
Smiles
O=C (NC1=NC=C (C=C1) C=2N=CC=NC2) CN3C=NC (C=4C=CN=C (C4) C (F) (F) F) =C3C
Molecular Formula
C21H16F3N7O
Molecular Weight
439.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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