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Zamaporvint

Zamaporvint (RXC004) is a potent, orally bioavailable porcupine inhibitor that suppresses Wnt signaling by blocking Wnt ligand palmitoylation and secretion. It has demonstrated anti-proliferative effects across diverse cancer cell lines in vitro and has shown anti-tumor activity in preclinical in vivo models.

Product Specifications

CAS Number

1900754-56-4

Product Name Alternative

Wnt, RXC 004, RXC004, RXC-004, Zamaporvint

Field of Research

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.50% (May vary between batches)

Solubility

DMSO:100 mg/mL (227.59 mM)

Smiles

O=C (NC1=NC=C (C=C1) C=2N=CC=NC2) CN3C=NC (C=4C=CN=C (C4) C (F) (F) F) =C3C

Molecular Formula

C21H16F3N7O

Molecular Weight

439.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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