Duostatin 5
Duostatin 5 (Duo-5) is a synthetic analog of the natural dolastatin 10 toxin, designed for constructing antibody-drug conjugates (ADCs) . It serves as a potent microtubule-disrupting payload in oncology research, enabling the evaluation of targeted therapies in both cellular and animal models.
Product Specifications
CAS Number
2124210-34-8
Product Name Alternative
ADCCytotoxin, ADC Cytotoxin, Antibody-Drug Conjugates (ADCs)
Purity
96.98% (May vary between batches)
Solubility
DMSO:100 mg/mL (129.53 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.18 mM)
Smiles
[C@H] ([C@H] (C (N[C@@H] (CC1=CC=C (N) C=C1) CN=[N+]=[N-]) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@H] (C (C) C) N (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C40H69N9O6
Molecular Weight
772.03
Storage Conditions
-20°C
Notes
For research use only.
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