Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
This small molecule linker, Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH, is a key component in constructing Antibody-Drug Conjugates (ADCs), such as the clinically used Deruxtecan payload. It enables the stable attachment of cytotoxic drugs to targeting antibodies for research in targeted cancer therapy, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1599440-20-6
Smiles
[C@H] (CC1=CC=CC=C1) (C (NCC (NCOCC (O) =O) =O) =O) NC (CNC (CN) =O) =O
Molecular Formula
C18H25N5O7
Molecular Weight
423.42
Storage Conditions
-20°C
Notes
For research use only.
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