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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

This small molecule linker, Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH, is a key component in constructing Antibody-Drug Conjugates (ADCs), such as the clinically used Deruxtecan payload. It enables the stable attachment of cytotoxic drugs to targeting antibodies for research in targeted cancer therapy, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1599440-20-6

Smiles

[C@H] (CC1=CC=CC=C1) (C (NCC (NCOCC (O) =O) =O) =O) NC (CNC (CN) =O) =O

Molecular Formula

C18H25N5O7

Molecular Weight

423.42

Storage Conditions

-20°C

Notes

For research use only.

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