Tz-Thalidomide
Tz-Thalidomide is a bifunctional molecule combining a tetrazine group with a thalidomide-based E3 ligase ligand. It exhibits affinity for BRD4 and is primarily used in chemical biology for targeted protein degradation studies, including PROTAC development and bioorthogonal labeling in cellular assays.
Product Specifications
CAS Number
2087490-42-2
Product Name Alternative
BRD4, Epigenetic Reader Domain, EpigeneticReaderDomain
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
98.34% (May vary between batches)
Solubility
DMSO:40 mg/mL (69.98 mM)
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (OCCCCCC (=O) NCC=4C=CC (=CC4) C5=NN=C (N=N5) C) C3C2=O) CC1
Molecular Formula
C29H29N7O6
Molecular Weight
571.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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