NLRP3-IN-17
NLRP3-IN-17 is a highly potent and selective oral inhibitor of the NLRP3 inflammasome, with an IC50 of 7 nM. It effectively blocks NLRP3-driven IL-1β release in vivo, providing a valuable research tool for investigating chronic inflammatory conditions such as gout, atherosclerosis, and Alzheimer's disease.
Product Specifications
CAS Number
2254432-75-0
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
N#CN=S (=O) (NC (=O) NC=1C2=C (C=C3C1CCC3) CCC2) C4=CC=C (C=C4) C
Molecular Formula
C21H22N4O2S
Molecular Weight
394.49
Storage Conditions
-20°C
Notes
For research use only.
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