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NLRP3-IN-17

NLRP3-IN-17 is a highly potent and selective oral inhibitor of the NLRP3 inflammasome, with an IC50 of 7 nM. It effectively blocks NLRP3-driven IL-1β release in vivo, providing a valuable research tool for investigating chronic inflammatory conditions such as gout, atherosclerosis, and Alzheimer's disease.

Product Specifications

CAS Number

2254432-75-0

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

N#CN=S (=O) (NC (=O) NC=1C2=C (C=C3C1CCC3) CCC2) C4=CC=C (C=C4) C

Molecular Formula

C21H22N4O2S

Molecular Weight

394.49

Storage Conditions

-20°C

Notes

For research use only.

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