Kras4B G12D-IN-1
Kras4B G12D-IN-1 is a selective small molecule inhibitor targeting the oncogenic Kras4B G12D mutant protein. It has been shown to reduce Kras protein expression in mutant-harboring MEFs in vitro and serves as a valuable chemical probe for studying KRAS-driven cancers in both cellular and animal models.
Product Specifications
CAS Number
2042365-85-3
Product Name Alternative
KRAS G12D
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.75% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.85 mM) ; DMSO:80 mg/mL (214.55 mM)
Smiles
C (=O) (C1=C (OC) C=CC (Cl) =C1) N2C[C@@H] (CNS (C=C) (=O) =O) CCC2
Molecular Formula
C16H21ClN2O4S
Molecular Weight
372.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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