S07-1066
S07-1066 is a selective AKR1C3 inhibitor that blocks the enzyme-mediated reduction of doxorubicin, thereby reversing chemoresistance in models with high AKR1C3 expression. This compound is a valuable research tool for studying doxorubicin resistance mechanisms and combination therapies in both cellular and animal cancer models.
Product Specifications
CAS Number
876625-29-5
Field of Research
Metabolism Research
Smiles
O=C (O) C1 (C=2C=CC (=C (F) C2) C3=CC (Cl) =CC (Cl) =C3) CC1
Molecular Formula
C16H11Cl2FO2
Molecular Weight
325.16
Storage Conditions
-20°C
Notes
For research use only.
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