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Lepzacitinib

Lepzacitinib is a selective small-molecule inhibitor targeting JAK1 and JAK3, developed for research into atopic dermatitis and inflammatory skin conditions. It is utilized in both in vitro and in vivo studies to investigate mechanisms of JAK-STAT pathway inhibition and its role in modulating immune-mediated inflammation.

Product Specifications

CAS Number

2321488-47-3

Product Name Alternative

ATI1777, ATI-1777

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.85% (May vary between batches)

Solubility

DMSO:80 mg/mL (225.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.29 mM)

Smiles

N (C1=C2C (=NC=C1C (OCC) =O) NC=C2) [C@H]3CN (C (CC#N) =O) CCC3

Molecular Formula

C18H21N5O3

Molecular Weight

355.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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