PB118
PB118 is a potent and selective HDAC6 inhibitor (IC50 = 5.6 nM) with multimodal activity relevant to Alzheimer's disease research. It promotes amyloid-beta clearance, stabilizes microtubules via tubulin acetylation, reduces neuroinflammation, and lowers phospho-tau levels in cellular and in vivo models.
Product Specifications
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
O=C (NO) C1=CC (F) =C (CN2CCCCC3=CC=CC=C32) C=C1
Molecular Formula
C18H19FN2O2
Molecular Weight
314.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARP71944_P050 100 µL
USP17L3 Antibody - C-terminal region (ARP71944_P050)
Sign In for Pricing
View Details 
EKC2560 1 Kit, Containing two 96 Well Plates and all necessary reagents
Casein Kinase I alpha (Phospho-Tyr294) Colorimetric Cell-Based ELISA Kit
Sign In for Pricing
View Details GTR15206304 1 Vial
Lentiviral mouse Cfl2 shRNA (UAS) - Lentiviral mouse Cfl2 shRNA (UAS, RFP) (100)
Sign In for Pricing
View Details orb1153147 100 µg
Mouse Monoclonal human TNFSF1A (TNF alpha) Antibody
Sign In for Pricing
View Details