PB118
PB118 is a potent and selective HDAC6 inhibitor (IC50 = 5.6 nM) with multimodal activity relevant to Alzheimer's disease research. It promotes amyloid-beta clearance, stabilizes microtubules via tubulin acetylation, reduces neuroinflammation, and lowers phospho-tau levels in cellular and in vivo models.
Product Specifications
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
O=C (NO) C1=CC (F) =C (CN2CCCCC3=CC=CC=C32) C=C1
Molecular Formula
C18H19FN2O2
Molecular Weight
314.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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