XE991
XE991 dihydrochloride is a selective Kv7 (KCNQ) channel blocker that potently inhibits Kv7.1, Kv7.2, and Kv7.2/7.3 heteromers, thereby suppressing the neuronal M-current. It is widely used in vitro and in vivo to investigate the role of these channels in epilepsy, pain, and cognitive disorders.
Product Specifications
CAS Number
122955-42-4
Product Name Alternative
Kv7.1, Kv7.2, PotassiumChannel, Potassium Channel
Field of Research
Pharmacology & Drug Discovery
Purity
98.87% (May vary between batches)
Smiles
O=C1C=2C=CC=CC2C (C=3C=CC=CC13) (CC=4C=CN=CC4) CC=5C=CN=CC5
Molecular Formula
C26H20N2O
Molecular Weight
376.45
Storage Conditions
-20°C
Notes
For research use only.
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