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EGFR-IN-85

EGFR-IN-85 is a potent and selective EGFR inhibitor with an IC50 of 0.19 μM against EGFRvIII phosphorylation. This compound effectively suppresses EGFR signaling in cellular models and has demonstrated activity in glioblastoma (GBM) research, including in vivo studies exploring its antitumor efficacy.

Product Specifications

CAS Number

1956378-29-2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

N (C=1N=C (N2C=3C (C=C2) =CC=CN3) C=CN1) C4=C (OC) C=C (N (CCN (C) C) C) C (NC (C=C) =O) =C4

Molecular Formula

C26H30N8O2

Molecular Weight

486.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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