EGFR-IN-85
EGFR-IN-85 is a potent and selective EGFR inhibitor with an IC50 of 0.19 μM against EGFRvIII phosphorylation. This compound effectively suppresses EGFR signaling in cellular models and has demonstrated activity in glioblastoma (GBM) research, including in vivo studies exploring its antitumor efficacy.
Product Specifications
CAS Number
1956378-29-2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C=1N=C (N2C=3C (C=C2) =CC=CN3) C=CN1) C4=C (OC) C=C (N (CCN (C) C) C) C (NC (C=C) =O) =C4
Molecular Formula
C26H30N8O2
Molecular Weight
486.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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