CK2-IN-9
CK2-IN-9 is a highly potent and selective CK2 kinase inhibitor with an enzyme IC50 of 3 nM and a cellular Wnt pathway IC50 of 75 nM. Its pharmacokinetic profile in rats is characterized by high clearance and low systemic exposure. This inhibitor is a valuable chemical probe for studying CK2 and Wnt signaling roles in cancer and cellular processes in both in vitro and in vivo models.
Product Specifications
CAS Number
1461658-58-1
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (#N) C1=C2N (C (NC3CC3) =CC (NC4=CC (NC (C) =O) =C (N (CCN (C) C) C) C=C4) =N2) N=C1
Molecular Formula
C23H29N9O
Molecular Weight
447.54
Storage Conditions
-20°C
Notes
For research use only.
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