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Sotuletinib dihydrochloride

Sotuletinib (BLZ945) dihydrochloride is a potent, brain-penetrant CSF1R inhibitor (IC50 = 1 nM) that induces tumor cell apoptosis. It has demonstrated significant anti-tumor efficacy in murine models and is a valuable research tool for studying cancer and neurodegenerative diseases like ALS in both in vitro and in vivo settings.

Product Specifications

CAS Number

2222138-40-9

Field of Research

Signal Transduction

Smiles

N (C=1SC=2C (N1) =CC=C (OC=3C=C (C (NC) =O) N=CC3) C2) [C@H]4[C@H] (O) CCCC4.Cl.Cl

Molecular Formula

C20H24Cl2N4O3S

Molecular Weight

471.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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