2′-Thioadenosine
2'-Thioadenosine (PD157432) is an irreversible, selective inhibitor that covalently modifies a cysteine residue in the active site of ErbB-1 and inhibits ErbB-2 tyrosine kinase with an IC50 of 45 μM. This small molecule is a valuable research tool for studying EGFR/Her2 signaling pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
136904-69-3
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
S[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (CO) [C@H]1O
Molecular Formula
C10H13N5O3S
Molecular Weight
283.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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