SJ1461
SJ1461 is a potent and orally bioavailable BET inhibitor, selectively targeting the BD1 and BD2 domains of BRD2 and BRD4 with low nanomolar IC50 values. It is a valuable chemical probe for investigating BET protein function in oncology and inflammation research, supporting both in vitro biochemical assays and in vivo efficacy studies.
Product Specifications
CAS Number
2924546-70-1
Field of Research
Epigenetics & Chromatin
Smiles
CC=1C2=C (N3C ([C@H] (CC (NC4=NN=CS4) =O) N=C2C5=CC=C (Cl) C=C5) =NN=C3C) SC1C
Molecular Formula
C21H18ClN7OS2
Molecular Weight
484
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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