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Dim16

Dim16 is a potent dual inhibitor of PCSK9 and HMG-CoAR, exhibiting IC50 values of 19 nM and 0.8 nM for PCSK9 enzyme inhibition and PCSK9-LDLR interaction blockade, respectively. This activity promotes increased LDL uptake in HepG2 cells, supporting research into dyslipidemia and atherosclerosis in both cellular and animal models.

Product Specifications

CAS Number

2743448-32-8

Field of Research

Protein Biochemistry

Smiles

IC1=NC=C (C2=NC=C (C=3C=CC=4C=CC=CC4C3) N2CCCC (C) (C) C) N1CCCCCNC

Molecular Formula

C29H38IN5

Molecular Weight

583.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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