Dim16
Dim16 is a potent dual inhibitor of PCSK9 and HMG-CoAR, exhibiting IC50 values of 19 nM and 0.8 nM for PCSK9 enzyme inhibition and PCSK9-LDLR interaction blockade, respectively. This activity promotes increased LDL uptake in HepG2 cells, supporting research into dyslipidemia and atherosclerosis in both cellular and animal models.
Product Specifications
CAS Number
2743448-32-8
Field of Research
Protein Biochemistry
Smiles
IC1=NC=C (C2=NC=C (C=3C=CC=4C=CC=CC4C3) N2CCCC (C) (C) C) N1CCCCCNC
Molecular Formula
C29H38IN5
Molecular Weight
583.55
Storage Conditions
-20°C
Notes
For research use only.
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